Histopathology

SR NO TEST TEST COMPONENTS METHOD SPECIMEN/TRANSPORT TAT CLINICAL APPLICATIONS
1 Special stains PAS stain-for fungal elements
ZN stain for acid fast bacilli
Manual Formalin fixed tissue 48 to 72 hrs, may be longer if longer bone decalcification required For detection of infective pathology
2 Immunohistochemistry study A) Undifferentiated malignant tumor (Basic localising Panel)*
· LCA
· Pan CK
· S100
· Vimentin
* Additional markers will be put after confirmation of initial lineage.
B) Metastatic adenocarcinoma of unknown primary
· CK7
· CK20
· PSA
· CA125
· GCDFP-15
· Hepar 1
· CDX2
· TTF1
· NAPSIN
· CK19
C) Metastatic squamoid carcinoma with unknown primary
· CK20
· CK7
· CK HMW
· EBV
· CD5
· P63
· P16
· CK 5/6
Leica BondMax fully automated IHC machine Formalin fixed tissue 3-4 days
May very if prolonged decalcificaiton required
For definitive diagnosis suspected on routine histopathology stain.
SR NO TEST TEST COMPONENTS METHOD SPECIMEN/TRANSPORT TAT CLINICAL APPLICATIONS